VSL#3® Capsules
VSL#3® Capsules
VSL#3® capsules are a gold standard in probiotics – trusted by healthcare professionals and patients for the dietary management of GI conditions and to support microbiota balance and digestive well-being.
- Stored and shipped cold to preserve potency
- 8 complementary probiotic strains from 3 genera
- Formulated for the dietary management of IBS and ulcerative colitis
BUNDLE & SAVE
Couldn't load pickup availability
VSL#3® Capsules
Free From Common Irritants:
Free From Common Irritants:
- Dairy-Free
- Gluten-Free
- Soy-Free
- Nut-Free
- No GMOs
- Vegan
Product Showcase
INGREDIENTS
- Probiotic strains: Streptococcus thermophilus, Bifidobacterium breve, Bifidobacterium lactis (previously classified as B. longum), Bifidobacterium lactis (previously classified as B. infantis), Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus helveticus (previously classified as L. delbrueckii subsp. bulgaricus)
- Other ingredients: Vegetal capsule (hydroxypropyl methylcellulose), cornstarch, magnesium stearate, silicon dioxide, stearic acid, microcrystalline cellulose.
HOW TO USE
Important Product Notice: VSL#3® is a medical food intended to be used under medical supervision.
Recommended Dosage
Typical adult dosage is 1–2 capsules up to 4 times daily, or as directed by a physician.
Administration & Notes
Swallow whole or mix into a non-carbonated cold beverage or food. Avoid consuming with hot foods or drinks, as heat may reduce probiotic viability.
Suggested Usage Cycle
Consistent use for several weeks may be needed to support microbiota balance.
Detailed Instructions Reference
For more information on how to take VSL#3® for the dietary management of certain GI conditions, please see the VSL#3® Product Information Sheet.
Probiotic Pioneer, Gut Health Leader.
VSL#3® is an ultra-high-potency probiotic medical food — and the #1 gastroenterologist-recommended multi-strain probiotics brand.
Developed for people with serious gastrointestinal conditions, it’s trusted by healthcare professionals and customers alike for its scientific foundation, clinical credibility, and unwavering quality.
Built on Science. Proven in Practice.
Driven by research — not marketing trends — VSL#3® is trusted in clinical care for the dietary management of specific gastrointestinal conditions. It continues to set the standard for potency, consistency, and reliability in probiotic therapy.
Ultra-High-Potency. Guaranteed.
VSL#3® products deliver between 112.5 billion and 900 billion live bacteria per serving, depending on the formulation. Unlike many probiotics that only promise potency at the time of manufacture, VSL#3® guarantees potency through expiration when stored as directed.
Clinically Researched Formulas.
Each VSL#3® product combines 8 well-characterized probiotic strains from 3 genera to help maintain a balanced intestinal microbiota and support digestive health. The VSL#3® family is specially designed for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and pouchitis.
It’s What’s on the Inside
Our unique 8-strain formulation is designed so each strain complements the others, helping maintain a balanced gut microbiota. Billions of live, beneficial bacteria work together to support digestive health.
-
Bifidobacterium
Bifidobacterium breve, Bifidobacterium lactis (previously classified as B. infantis), Bifidobacterium lactis (previously classified as B. longum)
-
Lactobacillus
Lactobacillus acidophilus, Lactobacillus helveticus (previously classified as L. delbrueckii subsp. bulgaricus), Lactobacillus paracasei, Lactobacillus plantarum
-
Streptococcus
Streptococcus thermophilus
Our Purpose: Science That Serves People
Gut microbiome health varies from person to person.
VSL® Probiotics connects microbiome research with daily wellness, creating targeted probiotic formulas to ease digestive issues and maintain intestinal & vaginal health.
Our flagship VSL#3® is a globally recognized medical-grade probiotic trusted by medical experts. Alongside series products for gut and vaginal care, we stick to high potency and strict quality standards, backed by clinical studies to advance microbiome science for professional medical use and daily health care.
The VSL® Difference: Proven. Precise. Trusted.
VSL® Probiotics builds on the legacy of VSL#3® — a formulation trusted by healthcare professionals for its quality, consistency, and reliability. That same foundation guides every product in the VSL® Probiotics family, from clinically studied medical foods to precision-formulated daily supplements.Our focus remains the same: creating probiotic formulations grounded in evidence, crafted with precision, and respected for their consistency — not driven by trends, but by trust earned through experience.
FAQs about VSL#3®
What is VSL#3®?
What is VSL#3®?
VSL#3® is an ultra-high-potency probiotic medical food intended for the dietary management of irritable bowel syndrome (IBS), ulcerative colitis (UC), and an ileal pouch (pouchitis).
How should I store VSL#3®?
How should I store VSL#3®?
VSL#3® should be stored under refrigeration at 36–46°F (2–8°C) to preserve potency. It can remain at room temperature for up to 2 weeks without reducing effectiveness.
What is a Medical Food?
What is a Medical Food?
Medical foods are formulated for the dietary management of diseases or conditions with distinctive nutritional needs that cannot be met by diet alone. Unlike dietary supplements, medical foods are intended for use under a healthcare provider's supervision.
How to use VSL Capsule？
How to use VSL Capsule？
Take this medicine in the dose and duration as advised by your doctor.VSL#3® Capsule may be taken with or without food
How does VSL#3® compare to a Low FODMAP diet for IBS management?
How does VSL#3® compare to a Low FODMAP diet for IBS management?
In a 2021 clinical study, VSL#3® demonstrated dietary management outcomes in people with IBS comparable to those achieved with a low FODMAP diet¹ — a commonly recommended but restrictive approach. Because VSL#3® is certified FODMAP Friendly, it can also be used alongside a low FODMAP diet for flexible dietary management.
¹Ankerson L, et al. J Med Internet Res. 2021; 23(12): e30291.
How are VSL#3® and VSL4® Gut different?
How are VSL#3® and VSL4® Gut different?
Although both products contain the same 8 probiotic strains, they are formulated and labeled for different purposes. VSL#3® is a refrigerated, ultra-high-potency probiotic medical food for the dietary management of specific GI conditions. VSL4® Gut is a probiotic supplement designed to support digestive comfort, regularity, and overall gut health.